Loader

Omics & Bioinformatics

Genomics, Proteomics, Metabolomics, Epigenetics, Microbiomics are all playing a critical role in supporting scientific research and development. Zifo has experience with the entire domain beginning with data management & orchestration, through pipelining and secondary analysis and on to visualisation and analytics across many sequencing and cell-based technologies.

ontology-development-governance

Ontology definition and governance in commercial and open-source platforms alongside deep domain and technical knowledge to support your FAIR and semantic data journey.

cell-mol-biol

Manipulation of biology at the 'Omic level and its downstream effects uses many different techniques such cloning, plasmid design, cell transfection and protein/product production.

epigenetics

Bioinformatics supporting genome-wide landscape of modifications such as DNA methylation, DNA-protein interactions, chromatin accessibility, histone modifications etc.

gene-expression

Spatial multiomics integration, Next Generation Sequencing (NGS), array based gene expression analysis, bulk and single-cell RNA-seq, epigenetic data integration, spatial transcriptomics.

genotyping

Exome and Whole Genome Sequence (WGS) variant calling and genome-wide association studies bioinformatics and data visualisation support

microbiome

16s/ITS Metagenomics & Meta-transcriptomics, pre-processing of raw data, dereplication of sequences and chimeric reads removal, OTU picking, Quality filtering, taxonomical classification

genome-editing

RNA-seq, scRNA-seq, or epigenome (e.g. ChIP-seq, Methylation sequencing) NGS or array-based, NGS-based analysis confirmation of genome edits at a targeted or genome-wide level, sgRNA design optimisation

translational-sciences

Bidirectional translation of biomedical knowledge from the early research laboratory, through development and manufacturing to clinical & patient-oriented and population-based research